Nothing is certain - but when we were about this many strips away from the end of volume 6 of Ma3, I was thinking (and saying) "They'll never wrap that up in the time, we're probably going to end the volume with the band hitting the stage". Giz and Dave do funny things with pacing sometimes.
However, sure, there's nothing I'd stake much money on. I'm currently envisaging some ambiguous stuff between Dillon and Julian, echoing the first three panels on
strip #151, followed by Ruby snuggling up to a happily stunned-looking Andy, thus echoing the fourth panel. But me typing that obviously makes it very unlikely. We could as easily get, say, some uncomfortable conversational stuff involving Dillon and Amber, followed by a shock reveal of Ray in bed with Julian... Or a completely different assortment of cast members.
And in any case, strip #150 only echoed strip #1 verbally ("Dilly... never change"/"Something's gotta change here" - which nicely exemplified the crucial difference between Amber and Ruby), so all we should be expecting is something akin to that. Maybe it'll just be Andy taking Ruby to a patisserie called "The Next Level", and her saying "Okay... I can breathe again now".